OrbiMed has invested in private healthcare companies since 1993.  OrbiMed seeks to be the capital provider of choice for healthcare companies seeking growth and new opportunities, and our team has helped to nurture and commercialize some of today's most successful healthcare companies.  The following companies represent our current private fund investments:

 


Acceleron Pharma

Acceleron Pharma

Developing therapeutics for metabolic and musculoskeletal diseases affecting millions of people


Acutus

Acutus

Developing a novel electro-anatomical mapping catheter for atrial fibrillation ablation procedures


Adimab

Adimab

Fully integrated yeast-based antibody discovery, maturation and production


Alector

Alector

Developing antibody therapeutics to treat neurodegenerative diseases


Ambit Biosciences

Ambit Biosciences

Discovering and developing small-molecule kinase inhibitors for the treatment of cancer


Anthera

Anthera

Developing and commercializing products to treat serious illnesses, including cardiovascular and autoimmune diseases


ARMO BioSciences

ARMO BioSciences

Focused on immuno-oncology


Arsanis Biosciences

Arsanis Biosciences

Developing antibody therapeutics for infectious diseases for which current prophylactic or therapeutic approaches are ineffective or nonexistent


Arteaus

Arteaus

Developing a CGRP antibody for the prevention of migraine


Audentes Therapeutics

Audentes Therapeutics

Developing gene therapies for orphan muscle diseases


Avitide

Avitide

Developing custom affinity purification solutions for the biopharmaceutical industry


Bacterin

Bacterin

Develops and manufactures bone graft substitutes and biologic allografts for use in orthopedic surgery


Biodel Inc.

Biodel Inc.

Developing innovative treatments for diabetes


CardiAQ

CardiAQ

Developing a TMVI system


Cardioxyl

Cardioxyl

Developing treatment for ADHF based on nitroxyl chemistry platform


Cerapedics

Cerapedics

Developing and commercializing products for the orthopedic bone substitutes market


Cleave Biosciences

Cleave Biosciences

Discovering and developing therapeutics targeting cellular protein homeostasis pathways


Clementia

Clementia

Clementia is a biopharmaceutical company focused on developing treatments for diseases of heterotopic ossification, including Fibrodysplasia Ossificans Progressiva (FOP).




DFine

DFine

Developing and marketing devices for vertebral compression fractures


Domain Surgical

Domain Surgical

Develops and commercializes a thermal surgical energy platform based on ferromagnetic technology


Durata Therapeutics

Durata Therapeutics

Developing dalbavancin for ABSSSI caused by susceptible gram-positive bacteria


Glaukos

Glaukos

Transforming glaucoma therapy


Good Start Genetics

Good Start Genetics

Developing improved methods of pre-pregnancy testing that utilizes advanced gene capture and sequencing technologies


Igenica

Igenica

Discovering and developing breakthrough antibody-based therapeutics for the treatment of cancer


Intercept

Intercept

Developing therapeutics for liver & metabolic diseases based on novel bile acid chemistry


Iroko Pharmaceuticals

Iroko Pharmaceuticals

Specialty pharmaceutical company focused on the development of non-steroidal anti-inflammatory drugs


Loxo Oncology

Loxo Oncology

Developing targeted cancer therapies for genetically-defined populations


MacroGenics

MacroGenics

Developing novel immunotherapeutics across multiple diseases


Mirati Therapeutics

Mirati Therapeutics

Mirati Therapeutics is a targeted oncology company developing an advanced pipeline of breakthrough medicines for precisely defined patient populations.


Natera

Natera

Provides preconception and prenatal genetic testing services including non-invasive prenatal testing


NxStage Medical

NxStage Medical

Commercializing products to significantly improve renal care


OmniGuide Surgical

OmniGuide Surgical

Develops and markets an advanced surgical energy delivery system with a line of flexible fiber-enabled CO₂ lasers


Otonomy

Otonomy

Developing novel drug therapies for disorders of the inner and middle ear


OxOnc Development

OxOnc Development

Conducting clinical studies of Xalkori in ROS1+ advanced NSCLC patients in Asia for Pfizer


Practice Fusion

Practice Fusion

Provides electronic health record services


Principia Biopharma

Principia Biopharma

Developing novel therapeutics using reversible covalent technology


Relypsa

Relypsa

Discovering and developing novel non-absorbed polymeric drugs for important applications in cardiovascular and renal diseases


Response BioMedical Corp.

Response BioMedical Corp.

Manufactures and markets rapid on-site diagnostic tests


Roka BioScience

Roka BioScience

Commercializing novel nucleic acid testing methods for industrial applications


Sage Therapeutics

Sage Therapeutics

Developing treatments for  rare and orphan diseases of the central nervous system


Selecta Biosciences

Selecta Biosciences

Developing first-in-class integrated synthetic nanoparticle vaccines


Sientra, Inc.

Sientra, Inc.

Developing products for the plastic surgery and aesthetics markets


Singulex

Singulex

Developing and commercializing the next generation of biomarker discovery and validation technologies


Sonendo

Sonendo

Developing innovative devices for root canal treatment


TELA Bio

TELA Bio

Developing novel biologic mesh implant products


TigerText

TigerText

Provides secure messaging in healthcare applications


Unilife

Unilife

Develops and supplies injectable drug delivery systems


ViewRay

ViewRay

Developing next generation radiotherapy technologies