OrbiMed has invested in private healthcare companies since 1993. OrbiMed seeks to be the capital provider of choice for healthcare companies at all stages of development, from start-up to growth equity stage. Our team has helped to nurture and commercialize some of today's most successful healthcare companies. The following companies represent our current private fund investments:


Acutus

Acutus

Developing a novel electro-anatomical mapping catheter for atrial fibrillation ablation procedures


Adimab

Adimab

Fully integrated yeast-based antibody discovery, maturation and production


Aerpio

Aerpio

Developing treatments for disorders of the vasculature with an initial emphasis on diabetic macular edema


Alector

Alector

Developing antibody therapeutics to treat neurodegenerative diseases


Ambit Biosciences

Ambit Biosciences

Discovering and developing small-molecule kinase inhibitors for the treatment of cancer


ARMO BioSciences

ARMO BioSciences

Discovering and developing novel immuno-oncology drugs


Arsanis Biosciences

Arsanis Biosciences

Developing antibody therapeutics for infectious diseases for which current prophylactic or therapeutic approaches are ineffective or nonexistent


Audentes Therapeutics

Audentes Therapeutics

Developing gene therapy products for rare diseases


Avitide

Avitide

Developing custom affinity purification solutions for the biopharmaceutical industry


Bacterin

Bacterin

Developing and manufacturing bone graft substitutes and biologic allografts for use in orthopedic surgery


CardiAQ

CardiAQ

Developing a TMVI system


Cardioxyl

Cardioxyl

Developing treatment for ADHF based on nitroxyl chemistry platform


Cerapedics

Cerapedics

Developing and commercializing products for the orthopedic bone substitutes market


Cleave Biosciences

Cleave Biosciences

Discovering and developing therapeutics targeting cellular protein homeostasis pathways


Clementia

Clementia

Developing treatments for diseases of heterotopic ossification, including Fibrodysplasia Ossificans Progressiva (FOP).




DFine

DFine

Developing and marketing devices for vertebral compression fractures


Dimension Therapeutics

Dimension Therapeutics

Developing AAV therapeutics for rare diseases


Domain Surgical

Domain Surgical

Develops and commercializes a thermal surgical energy platform based on ferromagnetic technology


Glaukos

Glaukos

Transforming glaucoma therapy


Good Start Genetics

Good Start Genetics

Developing improved methods of pre-pregnancy testing that utilizes advanced gene capture and sequencing technologies


Igenica

Igenica

Discovering and developing breakthrough antibody-based therapeutics for the treatment of cancer


Inspire Medical Systems

Inspire Medical Systems

Developed implanted neurostimulation device for Obstructive Sleep Apnea


Intercept

Intercept

Developing therapeutics for liver & metabolic diseases based on novel bile acid chemistry


Invitae

Invitae

Offering  genetic diagnostics for hereditary disorders


Iroko Pharmaceuticals

Iroko Pharmaceuticals

Specialty pharmaceutical company focused on the development of non-steroidal anti-inflammatory drugs


Loxo Oncology

Loxo Oncology

Developing targeted cancer therapies for genetically-defined populations


Mirati Therapeutics

Mirati Therapeutics

Developing a pipeline of breakthrough medicines for targeted patient populations


Natera

Natera

Provides preconception and prenatal genetic testing services including non-invasive prenatal testing


OmniGuide Surgical

OmniGuide Surgical

Develops and markets an advanced surgical energy delivery system with a line of flexible fiber-enabled CO₂ lasers


Otonomy

Otonomy

Developing novel drug therapies for disorders of the inner and middle ear


OxOnc Development

OxOnc Development

Conducting clinical studies of Xalkori in ROS1+ advanced NSCLC patients in Asia for Pfizer


Practice Fusion

Practice Fusion

A leading provider of electronic healthcare record services


Principia Biopharma

Principia Biopharma

Developing novel therapeutics using reversible covalent technology


ProNAi

ProNAi

Developing nucleic acid-based DNA interference technology for cancer and other diseases


Relypsa

Relypsa

Discovering and developing novel non-absorbed polymeric drugs for important applications in cardiovascular and renal diseases


Response BioMedical Corp.

Response BioMedical Corp.

Manufactures and markets rapid on-site diagnostic tests


Roka BioScience

Roka BioScience

Commercializing novel nucleic acid testing methods for industrial applications


Sage Therapeutics

Sage Therapeutics

Developing treatments for  rare and orphan diseases of the central nervous system


Selecta Biosciences

Selecta Biosciences

Developing first-in-class integrated synthetic nanoparticle vaccines


SI-Bone

SI-Bone

Commercializing the iFuse Implant System for minimally invasive sacroiliac joint fusions


Sientra, Inc.

Sientra, Inc.

Developing products for the plastic surgery and aesthetics markets


Singulex

Singulex

Developing and commercializing the next generation of biomarker discovery and validation technologies


Sonendo

Sonendo

Developing innovative devices for root canal treatment


Symbiomix Therapeutics

Symbiomix Therapeutics

A New Focus on Women's Health


TELA Bio

TELA Bio

Developing novel biologic mesh implant products


TigerText

TigerText

Provides secure messaging in healthcare applications


Unilife

Unilife

Develops and supplies injectable drug delivery systems


ViewRay

ViewRay

Developing next generation radiotherapy technologies