OrbiMed has invested in private healthcare companies since 1993. OrbiMed seeks to be the capital provider of choice for healthcare companies at all stages of development, from start-up to growth equity stage. Our team has helped to nurture and commercialize some of today's most successful healthcare companies. The following companies represent our current private fund investments:


Acutus

Acutus

Developing a novel electro-anatomical mapping catheter for atrial fibrillation ablation procedures


Adaptimmune

Adaptimmune

Focused on the use of T cell therapy to treat cancer and infectious disease


Adimab

Adimab

Fully integrated yeast-based antibody discovery, maturation and production


Aduro Biotech

Aduro Biotech

Clinical-stage cancer immunotherapy company with Breakthrough Therapy Designation


Aeglea Biotherapeutics

Aeglea Biotherapeutics

Developing novel treatments using engineered human amino acid degrading enzymes


Aerocrine AB

Aerocrine AB

Develops and markets tools to assist in the diagnosis and control of airways disease


Aerpio

Aerpio

Developing treatments for disorders of the vasculature with an initial emphasis on diabetic macular edema


Affimed

Affimed

Discovering and developing next generation antibody therapies


Aige Hospital

Aige Hospital

A leading eye hospital chain in the central region of China.


AIMS

AIMS

Multi-specialty tertiary care hospital in North India


AIT

AIT

Applied Immune Technologies (AIT) is a drug development company specializing in T-Cell Receptor-Like (TCRL) antibodies


AK Medical

AK Medical

A leader in joint replacement products and solutions in China


Alector

Alector

Developing antibody therapeutics to treat neurodegenerative diseases


Amoy Diagnostics

Amoy Diagnostics

The leader in cancer molecular diagnostics in China


arGEN-X

arGEN-X

Transforming antibody drug discovery with the product end game in mind.


ARMO BioSciences

ARMO BioSciences

Discovering and developing novel immuno-oncology drugs


Arsanis Biosciences

Arsanis Biosciences

Developing antibody therapeutics for infectious diseases for which current prophylactic or therapeutic approaches are ineffective or nonexistent


Arvinas

Arvinas

Arvinas is a pharmaceutical company focused on developing new small molecule strategies aimed at degrading disease-causing cellular proteins.


Ascendis Pharma

Ascendis Pharma

Ascendis Pharma develops differentiated prodrug versions using their proprietary TransCon technology. TransCon is used to generate product candidates that are improved versions of existing drugs.


Atox Bio

Atox Bio

Atox Bio is a late stage biotechnology company that develops novel immunomodulators to treat critically ill patients


Audentes Therapeutics

Audentes Therapeutics

Developing gene therapy products for rare diseases


Avedro, Inc.

Avedro, Inc.

Avedro is a privately held medical device and pharmaceutical company advancing the science and technology of corneal cross-linking and refractive correction

 


Avitide

Avitide

Developing custom affinity purification solutions for the biopharmaceutical industry


Balance Therapeutics

Balance Therapeutics

Balance Therapeutics is an R&D company focused on developing therapeutics to address conditions of intellectual disability


Bharat Serums and Vaccines

Bharat Serums and Vaccines

Developing and manufacturing a wide range of products such as plasma derivatives, hormones, antifungals, anaesthetics, cardiovascular and diagnostic products


BioLineRx

BioLineRx

Building a portfolio of products for various indications


Biotie Therapies

Biotie Therapies

Specialty pharmaceutical company focused on neurodegenerative and psychiatric disorders


Bonovo Orthopedics

Bonovo Orthopedics

Providing the latest orthopedic products to the Chinese healthcare community


CardiAQ

CardiAQ

Developing a TMVI system


Cardioxyl

Cardioxyl

Developing treatment for ADHF based on nitroxyl chemistry platform


cCAM Biotherapeutics

cCAM Biotherapeutics

Developing novel immunotherapies for different cancer indications


Cerapedics

Cerapedics

Developing and commercializing products for the orthopedic bone substitutes market


Cerenis Therapeutics

Cerenis Therapeutics

Discovering and developing breakthrough HDL-related therapies for the treatment of cardiovascular and metabolic diseases


Chemclin

Chemclin

A leader to provide affordable diagnostics products and solutions for infectious diseases and cancer testing in China.


Chemomab

Chemomab

Chemomab is developing therapeutic antibodies as potential treatments for inflammatory diseases


Cleave Biosciences

Cleave Biosciences

Discovering and developing therapeutics targeting cellular protein homeostasis pathways


Clementia

Clementia

Developing treatments for diseases of heterotopic ossification, including Fibrodysplasia Ossificans Progressiva (FOP).




Compass Therapeutics

Compass Therapeutics

Compass Therapeutics is seeking to cure various cancer types through their proprietary Targeted Immunomodulation platform


Corvus Pharmaceuticals

Corvus Pharmaceuticals

Developing novel immunotherapies for the treatment of cancer


Crown Bioscience

Crown Bioscience

A pre-clinical CRO with leadership in translational oncology and cancer drug discovery partnerships


DFine

DFine

Developing and marketing devices for vertebral compression fractures


DIH

DIH

A leading provider of robotics and intelligent systems for rehabilitation and medication care in China


Dimension Therapeutics

Dimension Therapeutics

Developing AAV therapeutics for rare diseases


Domain Surgical

Domain Surgical

Develops and commercializes a thermal surgical energy platform based on ferromagnetic technology


EA Inc.

EA Inc.

Commercializing transparent orthodontic products in China


EchoSens

EchoSens

French high-technology company specializing in non-invasive diagnostic products and services for hepatology


Ecron Acunova

Ecron Acunova

Providing clinical research services, including Clinical Trial Management, Clinical Data Management, PK/PD services and Central Lab


Eddingpharm

Eddingpharm

Commercializing a broad range of pharmaceutical products in high growth China markets


Futurx

Futurx

Pharma incubator established with J&J and Takeda. Supporting numerous projects sourced locally/internationally


GC Aesthetics

GC Aesthetics

Develops and manufactures breast and aesthetic implants for sale in over 90 countries


GC-Rise Pharmaceutical

GC-Rise Pharmaceutical

A leading Chinese pharmaceutical company focused on women and children's healthcare.


Genewiz

Genewiz

A leading global genomics service company


Glaukos

Glaukos

Transforming glaucoma therapy


Good Start Genetics

Good Start Genetics

Developing improved methods of pre-pregnancy testing that utilizes advanced gene capture and sequencing technologies


HLS Therapeutics

HLS Therapeutics

HLS Therapeutics is a specialty pharmaceutical company dedicating itself to acquiring and distributing commercial stage mature, or legacy, branded pharmaceutical drugs for the North American markets


Igenica

Igenica

Discovering and developing breakthrough antibody-based therapeutics for the treatment of cancer


Inspire Medical Systems

Inspire Medical Systems

Developed implanted neurostimulation device for Obstructive Sleep Apnea


Intellia Therapeutics

Intellia Therapeutics

Intellia is a leading gene editing company focused on the development of proprietary, potentially curative therapeutics utilizing a recently developed biological tool known as the CRISPR/Cas9 system


Intercept

Intercept

Developing therapeutics for liver & metabolic diseases based on novel bile acid chemistry


Invitae

Invitae

Offering  genetic diagnostics for hereditary disorders


Iroko Pharmaceuticals

Iroko Pharmaceuticals

Specialty pharmaceutical company focused on the development of non-steroidal anti-inflammatory drugs


Kala Pharmaceuticals

Kala Pharmaceuticals

Kala Pharmaceuticals is a clinical stage pharmaceutical company focused on innovative nanoparticle-based treatments for ocular diseases affecting both front and back of the eye


Keystone Heart

Keystone Heart

Developing procedural tools and accessories for use during TAVI and other complex percutaneous structural heart procedures.


KIMS GCC

KIMS GCC

A prominent chain of tertiary care hospitals and medical clinics in GCC


KIMS India

KIMS India

One of India's leading networks of tertiary care hospitals


Laxmi Dental

Laxmi Dental

Leading dental laboratory in India manufacturing dental crowns and bridges.


Loxo Oncology

Loxo Oncology

Developing targeted cancer therapies for genetically-defined populations


Marinus Pharmaceuticals

Marinus Pharmaceuticals

Marinus Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to the development of ganaxolone to improve the lives of patients suffering from CNS disorders


Medigus

Medigus

Developing innovative endoscopic procedures and devices


MID Labs

MID Labs

An innovative ophthalmic medical device company with customers from all over the world


Mirati Therapeutics

Mirati Therapeutics

Developing a pipeline of breakthrough medicines for targeted patient populations


Nabriva

Nabriva

Developing pleuromutilins, a new class of antibiotics addressing a significant medical need


Natera

Natera

Provides preconception and prenatal genetic testing services including non-invasive prenatal testing


NextCure

NextCure

NextCure is a biopharmaceutical company focused on discovering and developing next generation immuno-oncology-based drugs


Nucleix

Nucleix

Nucleix develops, manufactures and markets revolutionary non-invasive molecular cancer diagnostic tests


Nutrinia

Nutrinia

Nutrinia treats rare diseases of the GI tract by developing oral therapies that enhance GI absorption and functionality


ObsEva SA

ObsEva SA

ObsEva is a Swiss-based pharmaceutical company developing small molecule therapies for obstetric and gynecological conditions


OmniGuide Surgical

OmniGuide Surgical

Develops and markets an advanced surgical energy delivery system with a line of flexible fiber-enabled CO₂ lasers


ORIC Pharmaceuticals

ORIC Pharmaceuticals

ORIC Pharmaceuticals is focused on discovering and developing therapies to address treatment-resistant cancers.


Ornim Medical

Ornim Medical

Developing devices monitoring hemoglobin blood oxygen saturation


Otic Pharma

Otic Pharma

Developing novel formulations of ear antibiotics


Otonomy

Otonomy

Developing novel drug therapies for disorders of the inner and middle ear


OxOnc Development

OxOnc Development

Conducting clinical studies of Xalkori in ROS1+ advanced NSCLC patients in Asia for Pfizer


PharmAbcine

PharmAbcine

Developing fully human therapeutic antibodies for the treatment of cancer


Pieris AG

Pieris AG

Discovering and developing Anticalins®, a novel class of targeted protein therapeutics


PMV Pharma

PMV Pharma

Developing p53 modulators for the treatment of cancer


Practice Fusion

Practice Fusion

A leading provider of electronic healthcare record services


Principia Biopharma

Principia Biopharma

Developing novel therapeutics using reversible covalent technology


ProNAi

ProNAi

Developing nucleic acid-based DNA interference technology for cancer and other diseases


Rapid Pathogen Screening

Rapid Pathogen Screening

Marketer of rapid point-of-care diagnostic tests for inflammatory eye conditions


RDD Pharma

RDD Pharma

Developing drug-device combinations for the treatment of ano-rectal diseases


Realton Corporation

Realton Corporation

Developing diode-pumped laser systems for the treatment of enlarged prostate


Recro Pharma

Recro Pharma

Clinical stage specialty pharmaceutical company developing non-opioid therapeutics for the treatment of pain


Redhill Biopharma

Redhill Biopharma

Developing late clinical-stage formulations and combinations of existing drugs


Relypsa

Relypsa

Discovering and developing novel non-absorbed polymeric drugs for important applications in cardiovascular and renal diseases


Response BioMedical Corp.

Response BioMedical Corp.

Manufactures and markets rapid on-site diagnostic tests


Reviral

Reviral

ReViral is an emerging UK-based biopharma aiming to revitalize and transform the antiviral market by developing nove compounds


Rhythm Pharmaceuticals

Rhythm Pharmaceuticals

Rhythm is a biopharmaceutical company developing peptide therapeutics for the treatment of gastrointestinal (GI) diseases and obesity, including obesity caused by genetic deficiencies in the MC4 pathway


Roka BioScience

Roka BioScience

Commercializing novel nucleic acid testing methods for industrial applications


R-Pharm

R-Pharm

R-Pharm US is a specialty pharmaceutical company focused on the development and commercialization of medicines to treat cancer and chronic immune diseases


Sage Therapeutics

Sage Therapeutics

Developing treatments for  rare and orphan diseases of the central nervous system


Selecta Biosciences

Selecta Biosciences

Developing first-in-class integrated synthetic nanoparticle vaccines


Shasun

Shasun

Service provider to the global pharmaceutical industry, manufacturing and developing drug products and drug substances.


SI-Bone

SI-Bone

Commercializing the iFuse Implant System for minimally invasive sacroiliac joint fusions


Sientra, Inc.

Sientra, Inc.

Developing products for the plastic surgery and aesthetics markets


Sikka Software

Sikka Software

Enhancing practice economics and improving quality of care in the non-physician, non-hospital healthcare market through a cloud software platform


Singulex

Singulex

Developing and commercializing the next generation of biomarker discovery and validation technologies


Smartzyme

Smartzyme

SmartZyme Innovation is a Life Science company using a proprietary technology platform for protein design and engineering


Sonendo

Sonendo

Developing innovative devices for root canal treatment


Surya

Surya

A prominent neonatal and pediatric care hospital chain in Western India


Symbiomix Therapeutics

Symbiomix Therapeutics

A New Focus on Women's Health


Syndax Pharmaceuticals

Syndax Pharmaceuticals

Syndax is a late-stage biopharmaceutical company leveraging recent scientific insights in the emerging field of immuno-oncology


Synlogic

Synlogic

Synlogic engineers synthetic biotics, a new class of medicines to correct disease-causing metabolic dysregulation while operating within the microbiome


TELA Bio

TELA Bio

Developing novel biologic mesh implant products


TigerText

TigerText

Provides secure messaging in healthcare applications


Treato

Treato

The voice of the patient - big data analytics of patient online inputs


Tricida

Tricida

Pre-clinical stage biopharmaceutical company focused on the discovery and development of first-in-class therapeutics


True North

True North

Developing novel therapies that selectively inhibit the Complement system to treat rare diseases


Tyto

Tyto

TytoCare provides the missing link in telehealth - a digital examination tool and platform that connects patients at home to clinicians, to better inform their diagnoses


Unilife

Unilife

Develops and supplies injectable drug delivery systems


Upper Biotech

Upper Biotech

A leading POCT diagnostics company in China


ViewRay

ViewRay

Developing next generation radiotherapy technologies


Waterstone Pharmaceuticals

Waterstone Pharmaceuticals

China-based specialty pharmaceutical company


Whale Imaging

Whale Imaging

Developing and commercializing medical imaging solutions


Xtant Medical

Xtant Medical

Xtant Medical is a comprehensive supplier of orthopedic and spine surgery products


Zai Labratory

Zai Labratory

A leading biotech company based in China